Papers with enzyme-to-reaction and reaction-to-enzyme mapping
TIGER: Text-Informed Generalized Enzyme-Reaction Retrieval (2026.acl-long)
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| Challenge: | Existing approaches to enzyme–reaction retrieval suffer from poor generalization across tasks and distributions . TIGER is a text-informed generalized enzyme-reaction retrieval framework that bridges enzymes and biochemical reactions. |
| Approach: | They propose a text-informed generalized enzyme-reaction retrieval framework that leverages protein-to-text generation models to distill textual knowledge from enzyme sequences. |
| Outcome: | The proposed framework outperforms state-of-the-art methods in enzyme–reaction retrieval tasks and distributions. |